117614-91-2

Basic information

• Product Name: ethyl N-acetyl-O-p-toluenesulfonyl-2-amino-2-ethoxycarbonyl-5-hydroxypentanoate
• Synonyms: ethyl N-acetyl-O-p-toluenesulfonyl-2-amino-2-ethoxycarbonyl-5-hydroxypentanoate
• CAS NO: 117614-91-2
• Molecular Weight: 429.491
• Mol File: 117614-91-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl N-acetyl-O-p-toluenesulfonyl-2-amino-2-ethoxycarbonyl-5-hydroxypentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl N-acetyl-O-p-toluenesulfonyl-2-amino-2-ethoxycarbonyl-5-hydroxypentanoate(117614-91-2)
• EPA Substance Registry System: ethyl N-acetyl-O-p-toluenesulfonyl-2-amino-2-ethoxycarbonyl-5-hydroxypentanoate(117614-91-2)

Safety Data

• Hazardous Substances Data: 117614-91-2(Hazardous Substances Data)

Upstream product

• 1068-90-2 2-acetylaminomalonic acid diethyl ester 
• 53908-65-9 4-acetamido-4,4-bis(ethyloxycarbonyl)butyraldehyde 
• 53048-84-3 ethyl N-acetyl-2-amino-2-ethoxycarbonyl-5-hydroxypentanoate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 609-36-9 rac-Pro-OH 
• 542-32-5 (R,S)-2-aminoadipic acid 

Relevant articles and documents

Remarkable Nucleophilic Activity of N-Acetamido Group. Synthesis of Proline and Lysine for Biosynthetic Purposes

DL-Proline 7 was prepared from acroleine 1 and diethyl N-acetylaminomalonate 2 in 22percent overall yield.The key step was an intramolecular substitution of tosyloxy group in 4b by N-acetylamino group.The tosylate 4b was also an intermediate in synthesis of (6-13C) lysine.Pronounced differences in incorporation of (6-13C) and lysine to lupanine 12 were observed.