1176334-72-7

Upstream product

• 1176334-73-8 diethyl 2-(4-methylphenylsulfonamido)-3-phenyl-1,2-dihydroisoquinolin-1-ylphosphonate 
• 1112200-24-4 C₂₁H₁₆N₂O₂S 
• 762-04-9 phosphonic acid diethyl ester 
• 75586-32-2 2-phenylethynylbenzaldehyde p-toluenesulphonylhydrazone 
• 1353561-02-0 tert-butoxycarbonyl (3-phenylisoquinolinium-2-yl)amide 
• 106824-49-1 2-phenylethynylbenzaldehyde oxime 

Relevant academic research and scientific papers

An approach to 1-phosphorylated isoquinolines through silver(I)-catalyzed tandem reaction involving C-N and C-P bond formation

A novel silver-catalyzed tandem reaction of 2-alkynylbenzaldoximes with H-phosphinate esters, and H-phosphine oxides has been developed, providing a general and powerful tool for the synthesis of various 1-phosphorylated isoquinolins in moderate to excellent yield. This reaction proceeded smoothly to construct C-N and C-P bonds in one-pot with good functional group tolerance under mild conditions.

Lewis acid-catalyzed reactions of N′-(2-alkynylbenzylidene)hydrazides with diethyl phosphite

Lewis acid catalyst-tuned reactions of N′-(2-alkynylbenzylidene)hydrazides with diethyl phosphite are described. Isoquinolin-1-ylphosphonate is generated when copper triflate is utilized as catalyst, while 2-amino-1,2-dihydroisoquinolin-1-ylphosphonate is