117643-47-7

Upstream product

• 19790-60-4 3-Benzyloxypropanal 
• 13291-18-4 isopropenylmagnesium bromide 
• 557-93-7 2-bromoprop-1-ene 
• 4799-68-2 3-benzyloxypropan-1-ol 

Downstream Products

• 936642-07-8 C₁₃H₁₈O₂ 
• 1254369-09-9 C₂₁H₃₆O₂Si 
• 1254369-10-2 C₂₁H₃₈O₄Si 
• 1330118-88-1 (5R,6R)-5-(2-(benzyloxy)ethyl)-3,3-diethyl-6,11,11,12,12-pentamethyl-4,10-dioxa-3,11-disilatridecan-6-ol 
• 1254369-11-3 (8R,9R)-9-(2-(benzyloxy)ethyl)-11,11-diethyl-8-methoxy-2,2,3,3,8-pentamethyl-4,10-dioxa-3,11-disilatridecane 
• 1254369-13-5 C₃₄H₆₁NO₇Si₂ 
• 1254369-15-7 C₄₀H₇₅NO₇Si₃ 
• 1330118-89-2 (R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane 
• 1330118-68-7 (R)-5-((R)-3-(benzyloxy)-1-methoxypropyl)-2,2,3,3,5,10,10,11,11-nonamethyl-4,9-dioxa-3,10-disiladodecane 
• 1330118-75-6 (R)-4-benzyl-3-((2R,3S,5R,6R)-6,9-bis((tert-butyldimethylsilyl)oxy)-3-hydroxy-5-methoxy-2,6-dimethylnonanoyl)oxazolidin-2-one 
• 936642-29-4 C₂₄H₃₀O₄ 
• 936642-08-9 C₃₁H₃₈O₇S 
• 936642-05-6 C₂₅H₃₆N₄O₆S₂ 
• 936642-18-1 2-((4aS,5S,7S,8aR)-2,2,4a-trimethyl-7-((E)-4-((1-phenyl-1H-tetrazol-5-yl)sulfonyl)but-1-en-1-yl)hexahydropyrano[4,3-d]-[1,3]dioxin-5-yl)ethanol 

Relevant academic research and scientific papers

Total synthesis of (-)-4,8,10-tridesmethyl telithromycin

Novel sources of antibiotics are required to address the serious problem of antibiotic resistance. Telithromycin (2) is a third-generation macrolide antibiotic prepared from erythromycin (1) and used clinically since 2004. Herein we report the details of

Desmethyl macrolides: Synthesis and evaluation of 4,8,10-tridesmethyl telithromycin

There is an urgent need to discover new drugs to address the pressing problem of antibiotic resistance. Macrolide antibiotics such as erythromycin (1) are safe, broad-spectrum antibiotics used in the clinic since 1954. Herein, we report the synthesis and

Enantioselective total synthesis of macrolide antitumor agent (-)-lasonolide A

Equation presented An enantioselective total synthesis of (-)-lasonolide A is described. The upper tetrahydropyran ring was constructed stereoselectively by an intramolecular 1,3-dipolar cycloaddition reaction. The bicyclic isooxazoline led to the tetrahy