1176744-66-3 Usage
Uses
Used in Pharmaceutical Industry:
(2E,4E)-4-(4,4-DiMethyl-2-pentyn-1-ylidene)-2-pentenedioic Acid 1,5-DiMethyl Ester is used as a synthetic intermediate for the production of Terbinafine (T107500) derivatives. Terbinafine is a widely used antifungal medication, effective against a range of fungal infections. The compound's unique structure allows for the development of new therapeutic agents with improved efficacy and reduced side effects.
In the synthesis of Terbinafine derivatives, (2E,4E)-4-(4,4-DiMethyl-2-pentyn-1-ylidene)-2-pentenedioic Acid 1,5-DiMethyl Ester serves as a key building block, enabling the creation of novel antifungal agents with potential enhancements in pharmacokinetics, pharmacodynamics, and target specificity. This application highlights the importance of (2E,4E)-4-(4,4-DiMethyl-2-pentyn-1-ylidene)-2-pentenedioic Acid 1,5-DiMethyl Ester in the ongoing development of new treatments for fungal infections.
Check Digit Verification of cas no
The CAS Registry Mumber 1176744-66-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,6,7,4 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1176744-66:
(9*1)+(8*1)+(7*7)+(6*6)+(5*7)+(4*4)+(3*4)+(2*6)+(1*6)=183
183 % 10 = 3
So 1176744-66-3 is a valid CAS Registry Number.
1176744-66-3Relevant academic research and scientific papers
Novel stereoselective syntheses of (2E,4E)-4-(4,4-dimethylpent-2-ynylidene)-N1,N5-dimethyl-N1,N5-bis(naphthalen-1-ylmethyl)pent-2-ene-1,5-diamine
Colombo, Lino,Di Giacomo, Marcello,Serra, Massimo,Tambini, Simone M.
experimental part, p. 5838 - 5843 (2009/12/01)
We report two different synthetic approaches for the stereoselective synthesis of (2E,4E)-4-(4,4-dimethylpent-2-ynylidene)-N1,N5-dimethyl-N1,N5-bis(naphthalen-1-ylmethyl)pent-2-ene-1,5-diamine 1, an important im
