1176869-81-0

Basic information

• Product Name: 3-(4-fluorophenyl)-2-[(4-methoxyphenyl)sulfinyl]-1-benzofuran
• Synonyms: 3-(4-fluorophenyl)-2-[(4-methoxyphenyl)sulfinyl]-1-benzofuran
• CAS NO: 1176869-81-0
• Molecular Weight: 366.413
• Mol File: 1176869-81-0.mol

Chemical Properties

• CAS DataBase Reference: 3-(4-fluorophenyl)-2-[(4-methoxyphenyl)sulfinyl]-1-benzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-fluorophenyl)-2-[(4-methoxyphenyl)sulfinyl]-1-benzofuran(1176869-81-0)
• EPA Substance Registry System: 3-(4-fluorophenyl)-2-[(4-methoxyphenyl)sulfinyl]-1-benzofuran(1176869-81-0)

Safety Data

• Hazardous Substances Data: 1176869-81-0(Hazardous Substances Data)

Upstream product

• 271-89-6 1-benzofurane 
• 5335-87-5 4,4'-dimethoxyphenyl disulfide 
• 352-34-1 4-fluoro-1-iodobenzene 
• 1176869-73-0 2-[(4-methoxyphenyl)sulfinyl]-1-benzofuran 

Relevant articles and documents

Direct halosulfenylation of benzo[: B] furans: A metal-free synthesis of 3-halo-2-thiobenzo [b] furans

The first example of the direct halosulfenylation of benzo[b]furans with commercially available disulfides and N-halosuccinimides has been achieved, providing an efficient metal-free synthetic pathway to access diverse 3-halo-2-thiobenzo[b]furans in moderate to excellent yields. In particular, a halogen (e.g., bromo or iodo) substituent on the benzo[b]furan ring is amenable for further synthetic elaborations thereby broadening the diversity of the products.

2,3-Functionalization of furans, benzofurans and thiophenes via magnesiation and sulfoxide-magnesium exchange

The use of TMPMgCl·LiCl and iPrMgCl·LiCl allows a sequential 2,3-difunctionalization of various 2-arylsulfinyl furans, thiophenes and benzofurans. Subsequent use of the same reagents permits a selective full functionalization of all 4 positions of the fur