1177113-48-2Relevant academic research and scientific papers
Synthesis, Crystal Structure and Biological Activity of Novel N-substituted Diazabicyclo Derivatives
Ye, Fei,Wang, Chen,Ma, Peng,Zhao, Li-Xia,Gao, Shuang,Fu, Ying
, p. 335 - 341 (2018)
A series of N-substituted diazabicyclo derivatives were designed and synthesized based on the active subunit combination and structure–activity relationship theory. The compounds were prepared by levulinic acid or ester with diamine, then acylation with phenoxy acetyl chloride or acetoxy acetyl chloride. All the structures were characterized by IR, 1H NMR, 13C NMR, MS, and elemental analysis. The single crystal of compound 4a was determined by X-ray crystallography. The preliminary bioassay showed that all products could protect soybean against injury caused by 2,4-D butylate to some extent.
Synthesis, crystal structure, and bioactivity of N-dichloroacetyl diazabicyclo compounds
Ye, Fei,Li, Guan-Yu,Ding, Li,Fu, Ying,Xing, Zhi-Yong
, p. 75 - 78 (2013)
A short and efficient route to synthesis of a series of N -dichloroacetyl diazabicyclo derivatives has been developed. The compounds were obtained by cycloaddition of levulinic acid or ester with diamine, followed by acylation with dichloroacetyl chloride. All products were characterized by IR, 1H NMR, 13C NMR, MS, and elemental analysis. The single crystal of compound 4c was determined by X-ray crystallographic analysis. All compounds were tested for their herbicide safeners activity of protecting maize from injury with acetochlor.
Reaction of 4-oxocarboxylic acids and 5-substituted 3H-furan-2-ones with 1,2-binucleophiles of aromatic and alicyclic series
Grinev,Amal'Chieva,Egorova,Lyubun'
experimental part, p. 1378 - 1382 (2011/01/04)
Based on reactions of 5-substituted 3H-furan-2-ones or 4-oxocarboxylic acids with 1,2-binucleophiles of aromatic and aliphatic series methods were developed for the synthesis of tricyclic structures containing a pyrrolidine fragment fused with imidazolidine or oxazolidine ring. The pathways of the reactions are considered. It was demonstrated that the nature of the substrate did not affect the reaction direction, but changed the scheme of the interaction. The structures of compounds obtained for the first time were proved using IR and 1H NMR spectra.
