117721-77-4

Basic information

• Product Name: 2-Propen-1-ol, 3-[4-(1,1-dimethylethyl)phenyl]-, (E)-
• CAS NO: 117721-77-4
• Molecular Formula: C13H18O
• Molecular Weight: 190.285
• Mol File: 117721-77-4.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-ol, 3-[4-(1,1-dimethylethyl)phenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-ol, 3-[4-(1,1-dimethylethyl)phenyl]-, (E)-(117721-77-4)
• EPA Substance Registry System: 2-Propen-1-ol, 3-[4-(1,1-dimethylethyl)phenyl]-, (E)-(117721-77-4)

Safety Data

• Hazardous Substances Data: 117721-77-4(Hazardous Substances Data)

Upstream product

• 105393-26-8 ethyl 3-(4-t-butylphenyl) propenoate 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 27798-45-4 1-allyl-4-(tert-butyl)benzene 
• 86604-07-1 4-tert-butylcinnamaldehyde 
• 35779-04-5 1-tert-butyl-4-iodobenzene 
• 939-97-9 4-tert-Butylbenzaldehyde 
• 1208-65-7 4-tert-butyl-trans-cinnamic acid 
• 36215-20-0 methyl (E)-3-(4'-t-butylphenyl)-2-propenoate 
• 158010-17-4 ethyl (E)-3-[4-(tert-butylphenyl)]-2-propenoate 

Downstream Products

• 42006-42-8 (E)-1-(tert-butyl)-4-(prop-1-en-1-yl) benzene 
• 86604-07-1 4-tert-butylcinnamaldehyde 
• 149169-92-6 (E)-1-(3-bromoprop-1-en-1-yl)-4-(tert-butyl)benzene 
• 1300698-79-6 (E)-5-(4-(tert-butyl)phenyl)pent-4-enoic acid 

Relevant articles and documents

Palladium-Catalyzed Allyl-Allyl Reductive Coupling of Allylamines or Allylic Alcohols with H2as Sole Reductant

Catalytic carbon-carbon bond formation building on reductive coupling is a powerful method for the preparation of organic compounds. The identification of environmentally benign reductants is key for establishing an efficient reductive coupling reaction. Herein an efficient strategy enabling H2 as the sole reductant for the palladium-catalyzed allyl-allyl reductive coupling reaction is described. A wide range of allylamines and allylic alcohols as well as allylic ethers proceed smoothly to deliver the C-C coupling products under 1 atm of H2. Kinetic studies suggested that the dinuclear palladium species was involved in the catalytic cycle.

Synthesis of Allylsilanes via Nickel-Catalyzed Cross-Coupling of Silicon Nucleophiles with Allyl Alcohols

NiCl2(PMe3)2-catalyzed reaction of allyl alcohols with silylzinc reagents, including PhMe2SiZnCl, Ph2MeSiZnCl, and Ph3SiZnCl, was performed, achieving allylsilanes in high yields. Aryl- and heteroaryl-substituted allyl alcohols, (E)-3-arylprop-2-en-1-ols, 1-aryl-prop-2-en-1-ols, and (E)-1-phenylpent-1-en-3-ol can be employed in the transformation. A range of functional groups as well as heteroaryl groups were tolerated. Reaction exhibited high regioselectivity and E/Z-selectivity when 1- or 3-aryl-substituted allyl alcohols were used as the substrates. Reaction of chiral allyl alcohol, (S,E)-1-phenylpent-1-en-3-ol, yielded a configuration-inversion product (R,E)-dimethyl(phenyl)(1-phenylpent-1-en-3-yl)silane.

Copper-Catalyzed Perfluoroalkylation of Allyl Phosphates with Stable Perfluoroalkylzinc Reagents

A general and practical method for copper-catalyzed cross-coupling of allyl phosphates with stable perfluoroalkylzinc reagents has been developed. The reaction proceeds under mild reaction conditions with high efficiency, good functional group tolerance, and high regio- A nd stereoselectivities and provides general, straightforward, and useful access to allyl-perfluoroalkyl compounds. Preliminary mechanistic studies reveal that the allyl copper intermediate may be involved in the catalytic cycle.