Cas 1177418-30-2,4-[3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl]-N-(1(S)-phenylethyl)pyridin-2-amine

1177418-30-2

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Basic information

Product Name: 4-[3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl]-N-(1(S)-phenylethyl)pyridin-2-amine
Synonyms:
CAS NO:1177418-30-2
Molecular Formula:
Molecular Weight: 401.483
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 4-[3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl]-N-(1(S)-phenylethyl)pyridin-2-amine(CAS DataBase Reference)
NIST Chemistry Reference: 4-[3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl]-N-(1(S)-phenylethyl)pyridin-2-amine(1177418-30-2)
EPA Substance Registry System: 4-[3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl]-N-(1(S)-phenylethyl)pyridin-2-amine(1177418-30-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1177418-30-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1177418-30-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,7,4,1 and 8 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1177418-30:
(9*1)+(8*1)+(7*7)+(6*7)+(5*4)+(4*1)+(3*8)+(2*3)+(1*0)=162
162 % 10 = 2
So 1177418-30-2 is a valid CAS Registry Number.

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1177418-30-2Relevant academic research and scientific papers

3,4-Diaryl-isoxazoles and -imidazoles as potent dual inhibitors of p38α mitogen activated protein kinase and casein kinase 1δ

Peifer, Christian,Abadleh, Mohammed,Bischof, Joachim,Hauser, Dominik,Schattel, Verena,Hirner, Heidrun,Knippschild, Uwe,Laufer, Stefan

, p. 7618 - 7630 (2009)

In this study, we report on the discovery of isoxazole 1 as a potent dual inhibitor of p38α (IC50 = 0.45 μM) and CK1δ (IC 50 = 0.23 μM). Because only a few effective small molecule inhibitors of CK1 have been described so far, we aim

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