1177447-87-8

Basic information

• Product Name: 4-(2-tert-butoxyethoxy)-5-(2-methoxyphenoxy)-6-chloro-2,2'-bipyrimidine
• Synonyms: 4-(2-tert-butoxyethoxy)-5-(2-methoxyphenoxy)-6-chloro-2,2'-bipyrimidine
• CAS NO: 1177447-87-8
• Molecular Weight: 430.891
• Mol File: 1177447-87-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(2-tert-butoxyethoxy)-5-(2-methoxyphenoxy)-6-chloro-2,2'-bipyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-tert-butoxyethoxy)-5-(2-methoxyphenoxy)-6-chloro-2,2'-bipyrimidine(1177447-87-8)
• EPA Substance Registry System: 4-(2-tert-butoxyethoxy)-5-(2-methoxyphenoxy)-6-chloro-2,2'-bipyrimidine(1177447-87-8)

Safety Data

• Hazardous Substances Data: 1177447-87-8(Hazardous Substances Data)

Upstream product

• 7580-85-0 tert-butyl glycidyl ether 
• 150728-13-5 4,6-dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine 

Downstream Products

• 301646-60-6 N-[6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)benzenesulfonamide 
• 184779-15-5 2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy) ethanol 
• 1160515-45-6 2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol formyl ether 

Relevant articles and documents

PROCESS FOR PREPARING BOSENTAN

The present invention relates to a novel intermediate useful in the preparation of bosentan and to processes for the preparation of said intermediate and bosentan. The invention further relates to compositions comprising bosentan prepared according to the processes of the invention and their use in the treatment of endothelin-receptor mediated disorders.