117757-68-3

Basic information

• Product Name: 3,5-Dichloro-4-iodobenzoic acid
• Synonyms: 3,5-Dichloro-4-iodobenzoic acid
• CAS NO: 117757-68-3
• Molecular Formula: C₇H₃Cl₂IO₂
• Molecular Weight: 316.90799
• Mol File: 117757-68-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,5-Dichloro-4-iodobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dichloro-4-iodobenzoic acid(117757-68-3)
• EPA Substance Registry System: 3,5-Dichloro-4-iodobenzoic acid(117757-68-3)

Safety Data

• Hazardous Substances Data: 117757-68-3(Hazardous Substances Data)

Usage

Uses

3,5-Dichloro-4-iodobenzoic acid is a useful reagent in the preparation of substituted spiroxazolidinones as somatostatin subtype receptor 5 (SSTR5) antagonists.

Upstream product

• 78473-00-4 4-amino-3,5-dichlorobenzonitrile 
• 651058-99-0 methyl 3,5-dichloro-4-iodobenzoate 

Downstream Products

• 1350760-15-4 2,6-dichloro-4'-fluorobiphenyl-4-carboxaldehyde 
• 1350758-55-2 4-{8-[(2,6-dichloro-4'-fluorobiphenyl-4-yl)methyl]-1-oxa-2,8-diazaspiro[4.5]dec-2-en-3-yl}benzoic acid trifluoroacetate 
• 51-36-5 3,5-dichlorobenzoic acid 
• 1350760-11-0 2,6-dichloro-4'-fluorobiphenyl-4-carboxylic acid 

Relevant articles and documents

BIARYL COMPOUND, PREPARATION METHOD AND USE THEREFOR

The present invention belongs to the technical field of chemical pharmaceuticals, and relates to a compound represented by general formula (I) or formula (II) and a preparation method thereof. The compounds are biaryl derivatives with RORγt activation activity. The biaryl derivatives disclosed in this invention can effectively activate the RORγt protein receptor, and thereby promote the differentiation of Th17 cells and increasing the production of IL-17, which can be used as an immune modulator for the treatment of various cancers or viral infection-related diseases.