117804-02-1Relevant academic research and scientific papers
Isolation of 4,4'-Dimethoxy-trans-stilbene and Flavonoids from Leaves and Twigs of Vitex negundo Linn.
Banerji, J.,Das, B.,Chakrabarty, R.,Jha, H. C.
, p. 597 - 599 (2007/10/02)
The leaves and twigs of Vitex negundo Linn. afford a stilbene derivative characterised as 4,4'-dimethoxy-trans-stilbene (1), along with five flavones, 5,6,7,8,3',4',5'-heptamethoxy (2), 5-hydroxy-6,7,8,3',4'-pentamethoxy (5-O-desmethylnobiletin) (3), 5-hydroxy-6,7,8,3',4',5'-hexamethoxy (gardenin A) (4), 5-hydroxy-6,7,8,4'-tetramethoxy (gardenin B) (5) and 5-hydroxy-7,3',4',5'-tetramethoxyflavone (corymbosin) (6).This is the first report of 1 as a natural product.Compound 1 has been converted into 3,6-dimethoxyphenanthrene (11).The flavones 2,5 and 6 undergo interesting rearrangements when treated with hydrazine hydrate to generate the pyrazoles 14, 15 and 16 respectively.
