117857-85-9Relevant academic research and scientific papers
Evolution of chiral Lewis basic N-formamide as highly effective organocatalyst for asymmetric reduction of both ketones and ketimines with an unprecedented substrate scope
Zhou, Li,Wang, Zhouyu,Wei, Siyu,Sun, Jian
, p. 2977 - 2979 (2008/02/12)
L-Pipecolinic acid derived Lewis basic N-formamide 5e has been developed as a first highly effective catalyst for the asymmetric reduction of aromatic and aliphatic ketones as well as aromatic and aliphatic ketimines in good to high enantioselectivity. The Royal Society of Chemistry.
Stereoselective Addition Reaction of Organolithium Reagents to Chiral Imines Derived from erythro-2-Amino-1,2-diphenylethanol
Hashimoto, Yukihiko,Takaoki, Kazuo,Sudo, Atsushi,Ogasawara, Tsuneo,Saigo, Kazuhiko
, p. 235 - 236 (2007/10/02)
The chiral imines prepared from an artificial chiral auxiliary, erythro-2-amino-1,2-diphenylethanol, and various aldehydes, reacted with organolithium reagents to give the corresponding chiral amines with excellent diastereofacial selectivity.
Studies on reaction conditions and new entry to chiral ligands in the chiral lithium amide-mediated enantioselective aldol reaction
Ando,Tatematsu,Shioiri
, p. 1967 - 1971 (2007/10/02)
Reaction conditions for the enantioselective aldol reaction of 2,2-dimethyl-3-pentanone (3) and benzaldehyde using the chiral lithium amide 1b as a chiral auxiliary were thoroughly investigated. All three procedures, that is, (1) the combined use of lithi
