23364-45-6Relevant academic research and scientific papers
Diastereoselective Michael addition of 2H-2-oxo-1,4,2-oxaza phosphinanes to olefins
Monbrun, Jér?me,Dayde, Bénédicte,Cristau, Henri-Jean,Volle, Jean-No?l,Virieux, David,Pirat, Jean-Luc
scheme or table, p. 540 - 545 (2011/03/18)
Diastereoselective Michael additions of 2-hydrogeno-2-oxo-1,4,2- oxazaphosphinanes to olefins were described. Phosphinopeptide compounds were obtained in very good yield (up to 90%) and diasteromeric excesses ranging from 26 to 78%. Copyright
Evolution of chiral Lewis basic N-formamide as highly effective organocatalyst for asymmetric reduction of both ketones and ketimines with an unprecedented substrate scope
Zhou, Li,Wang, Zhouyu,Wei, Siyu,Sun, Jian
, p. 2977 - 2979 (2008/02/12)
L-Pipecolinic acid derived Lewis basic N-formamide 5e has been developed as a first highly effective catalyst for the asymmetric reduction of aromatic and aliphatic ketones as well as aromatic and aliphatic ketimines in good to high enantioselectivity. The Royal Society of Chemistry.
Synthesis, reactivity and stereochemistry of new phosphorus heterocycles with 5- or 6-membered rings
Cristau, Henri-Jean,Pirat, Jean-Luc,Virieux, David,Monbrun, Jér?me,Ciptadi, Ciptadi,Bekro, Yves-Alain
, p. 2472 - 2481 (2007/10/03)
Syntheses of novel phosphorus heterocycles containing α-amino or α-hydroxyphosphonic or phosphinic acids motifs are developed. 2,3-dihydro-1,3-oxaphospholes (1) and 1,4,2-oxazaphosphinanes (2) exhibit a reactive part, respectively the enolether moiety and the P-H bond, which allows various structural modifications: (i) for 1a, by introduction of amino substituents, (ii) for 2a, by hydroxy- or aminoalkylation, by Michael addition or by P-arylation. These reactions present generally a good or even an excellent kinetic diastereoselectivity which can often be predicted by molecular models of the transition states.
Easily accessible chiral amino-phosphinite ligands for highly enantioselective palladium-mediated allylic alkylation
Chen, Guoshu,Li, Xin,Zhang, Haile,Gong, Liuzhu,Mi, Aiqiao,Cui, Xin,Jiang, Yaozhong,Choi, Michael C.K.,Chan, Albert S.C.
, p. 809 - 813 (2007/10/03)
Palladium-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate with the dimethyl malonate-BSA-LiOAc system has been successfully carried out in the presence of easily prepared new chiral amino-phosphinite ligands such as 3b and 3c to
