117872-48-7

Upstream product

• 60857-16-1 N-(4-methoxybenzyl)glycine ethyl ester 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 117872-49-8 1-(4-methoxybenzyl)piperazine-2,5-dione 
• 104124-06-3 5-methoxy-1-(4-methoxybenzyl)-3,6-dihydropyrazin-2(1H)-one 
• 117856-56-1 3-<3'-(dimethyl-t-butylsilyloxy)-1'-methylenepropyl>-5-methoxy-1-(4-methoxybenzyl)-3,6-dihydropyrazin-2(1H)-one 
• 104124-10-9 3-<4'-hydroxy-1'-(p-tolylsulphonyl)-2'-trimethylsilylbutan-2'-yl>-5-methoxy-1-(4-methoxybenzyl)-3,6-dihydropyrazin-2(1H)-one 
• 104124-08-5 3-[3-(tert-Butyl-dimethyl-silanyloxy)-1-(toluene-4-sulfonylmethyl)-1-trimethylsilanyl-propyl]-5-methoxy-1-(4-methoxy-benzyl)-3,6-dihydro-1H-pyrazin-2-one 
• 104124-12-1 9-methoxy-8-(4-methoxybenzyl)-5-trimethylsilyl-5-<(p-tolylsulphonyl)methyl>-2-oxa-8,10-diazabicyclo<4.2.2>dec-9-en-7-one 
• 104124-12-1 9-methoxy-8-(4-methoxybenzyl)-5-trimethylsilyl-5-<(p-tolylsulphonyl)methyl>-2-oxa-8,10-diazabicyclo<4.2.2>dec-9-en-7-one 

Relevant academic research and scientific papers

Synthetic Studies on Bicyclomycin and its Analogues. Part 1. Synthesis of Substituted 2-Oxa-8,10-diazabicyclodecanes

Methods have been developed for formation of the eight-membered oxygen-containing ring system (2) present in the antibiotic bicyclomycin.The procedure starts with N,N'-disubstituted piperazine-2,5-diones or the corresponding mono imino ethers.A new method is based on the oxidation of the mono imino ethers using 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) as oxidant: the bis imino ethers gave pyrazines under these conditions, whilst the parent piperazinedione proved to be unreactive.