117887-41-9

Basic information

• Product Name: 1H-Indol-3-ol, 5-bromo-4-chloro-
• Synonyms: 1H-Indol-3-ol, 5-bromo-4-chloro-;1H-Indol-3-ol,5-broMo-4-chloro-,N-Boc;5-bromo-4-chloro-1H-Indol-3-ol
• CAS NO: 117887-41-9
• Molecular Formula: C₈H₅BrClNO
• Molecular Weight: 246.4884
• Mol File: 117887-41-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 437.863 °C at 760 mmHg
• Flash Point: 218.612 °C
• Appearance: /
• Density: 1.919 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.763
• CAS DataBase Reference: 1H-Indol-3-ol, 5-bromo-4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indol-3-ol, 5-bromo-4-chloro-(117887-41-9)
• EPA Substance Registry System: 1H-Indol-3-ol, 5-bromo-4-chloro-(117887-41-9)

Safety Data

• Hazardous Substances Data: 117887-41-9(Hazardous Substances Data)

Usage

General Description

1H-Indol-3-ol, 5-bromo-4-chloro- is a chemical compound with the molecular formula C8H5BrClNO. It is a derivative of indole, a heterocyclic aromatic organic compound. 1H-Indol-3-ol, 5-bromo-4-chloro- contains both bromine and chlorine atoms, as well as a hydroxyl group attached to the indole ring. It is commonly used as a building block in organic synthesis and pharmaceutical research, due to its potential for creating novel chemical structures with biological activity. Its unique combination of functional groups makes it a valuable tool for the development of new drugs and materials.

InChI:InChI=1/C8H5BrClNO/c9-4-1-2-5-7(8(4)10)6(12)3-11-5/h1-3,11-12H

Upstream product

• 7240-90-6 5-bromo-4-chloro-3-indolyl β-D-galactopyranoside 

Downstream Products

• 29245-44-1 5,5'-dibromo-4,4'-dichloro-1H,1'H-[2,2']biindolylidene-3,3'-dione 

Relevant articles and documents

PH responsive Janus-like supramolecular fusion proteins for functional protein delivery

A facile, noncovalent solid-phase immobilization platform is described to assemble Janus-like supramolecular fusion proteins that are responsive to external stimuli. A chemically postmodified transporter protein, DHSA, is fused with (imino)biotinylated cargo proteins via an avidin adaptor with a high degree of spatial control. Notably, the derived heterofusion proteins are able to cross cellular membranes, dissociate at acidic pH due to the iminobiotin linker and preserve the enzymatic activity of the cargo proteins β-galactosidase and the enzymatic subunit of Clostridium botulinum C2 toxin. The mix-and-match strategy described herein opens unique opportunities to access macromolecular architectures of high structural definition and biological activity, thus complementing protein ligation and recombinant protein expression techniques.

A kinetic study of the acid-catalyzed hydrolysis of some indolyl-beta-D-glucopyranosides.

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