117894-23-2Relevant articles and documents
Enantiodivergent preparation of optically pure tricyclic cyclohexanoids via lipase-mediated asymmetrization of a meso-symmetric starting material
Moriya,Kamikubo,Ogasawara
, p. 187 - 190 (1995)
Two potentially useful, optically pure, tricyclohexanoids having 1,4-ethanohydronaphthalen-5-one system have been prepared in an enantiodivergent way from a single chiral tricyclic cyclohexanoid precursor obtained by lipase-mediated asymmetrization of a m
Enantioselective Synthesis of cis-Decalin Derivatives by the Inverse-Electron-Demand Diels–Alder Reaction of 2-Pyrones
Cai, Quan,Li, Zhan-Ting,Si, Xu-Ge,Zhang, Zhi-Mao,Zheng, Cheng-Gong
supporting information, p. 18412 - 18417 (2020/08/21)
A novel strategy for the synthesis of cis-decalins by an ytterbium-catalyzed asymmetric inverse-electron-demand Diels–Alder reaction of 2-pyrones and silyl cyclohexadienol ethers is reported here. A broad range of synthetically important cis-decalin derivatives with multiple contiguous stereogenic centers and functionalities are obtained in good yields and stereoselectivities. A full set of diastereomeric substituted cis-decalin motifs are readily accessible by tuning the absolute configurations of substituted silyl cyclohexadienol ethers (R or S) as well as the ligands (R or S). The synthetic potential is showcased by the enantioselective total synthesis of 4-amorphen-11-ol, and further demonstrated by the first total synthesis of cis-crotonin.
A simple asymmetric organocatalytic approach to optically active cyclohexenones
Carlone, Armando,Marigo, Mauro,North, Chris,Landa, Aitor,Jorgensen, Karl Anker
, p. 4928 - 4930 (2007/10/03)
Optically active 2,5-disubstituted-cyclohexen-2-one derivatives have been prepared in a one-pot process consisting of five reaction steps: an organocatalytic asymmetric conjugated addition of β-ketoesters to α,β-unsaturated aldehydes that proceeds in aque
