1178958-75-2

Upstream product

• 768-35-4 3-fluorophenylboronic acid 
• 146328-85-0 5-bromo-2-fluoro-benzoic acid 

Downstream Products

• 1427330-96-8 ethyl 2-[2,4-difluoro-3-[[2-fluoro-5-(3-fluorophenyl)benzoyl]amino]phenoxy]acetate 
• 1427330-86-6 2-[2,4-difluoro-3-[[2-fluoro-5-(3-fluorophenyl)phenyl]methylamino]phenoxy] acetic acid 
• 1427330-88-8 ethyl 2-[2,4-difluoro-3-[[2-fluoro-5-(3-fluorophenyl)phenyl]methyl amino]phenoxy]acetate 
• 1427330-89-9 isopropyl 2-[2,4-difluoro-3-[[2-fluoro-5-(3-fluorophenyl)phenyl]methylamino]phenoxy]acetate 
• 1427406-58-3 C₂₂H₁₇F₄NO₃ 
• 1427408-35-2 C₂₅H₂₃F₄NO₃ 
• 1427408-34-1 (R,S)-2,4-difluoro-3-[1-[2-fluoro-5-(3-fluorophenyl)phenyl]ethylamino]phenol 
• 1427408-33-0 2,4-difluoro-3-[(E)-1-[2-fluoro-5-(3-fluorophenyl)phenyl]ethylideneamino]phenol 
• 1427406-45-8 C₂₅H₂₁F₄NO₅ 
• 1427406-44-7 C₂₅H₂₃F₄NO₅ 
• 1427406-43-6 C₂₆H₂₅F₄NO₆ 
• 1427406-42-5 C₂₃H₂₀F₄N₂O₂ 
• 1427406-41-4 C₂₁H₁₆F₄N₂O₂ 
• 1427406-40-3 C₂₇H₂₆F₄N₂O₄ 

Relevant academic research and scientific papers

Bi-aryl derivatives, their preparation and their therapeutic application

Bi-aryl derivatives of formula (I), their preparation and their therapeutic application as EP2 agonists in, for example, glaucoma. or one of its prodrugs, in which: R1 represents, independently from each other, H or an halogen, R2 represents H, an halogen, or a (C1-C6)alkyl, R3 represents, independently from each other, H, an halogen, -OH, or a (C1-C6)alkyl.

ANILINE DERIVATIVES,THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

The present invention relates to aniline derivatives, to their preparation and to their therapeutic application.

2-(3-aminophenoxy)-acetic acid derivatives as EP2 receptor agonists for use in treatment of glaucoma

Aniline derivatives, their preparation and their therapeutic application as EP2 agonists in, for example, glaucoma. R1 represents, independently from each other, H, a (C1-C6) alkyl or an halogen, R2 represents H, an halogen, or a (C1-C6) alkyl, R3 represents, independently from each other, H, an halogen, -OH, -O-(C1-C6) alkyl or a -(C1-C6) alkyl.

THERAPEUTIC AGENTS FOR TREATMENT OF OCULAR HYPERTENSION

The invention provides well-defined amides for treating glaucoma and ocular hypertension.