117901-57-2

Upstream product

• 15981-92-7 2,3'-anhydrothymidine 
• 23974-72-3 sodium phenylselenide 
• 1666-13-3 diphenyl diselenide 
• 7481-90-5 3',4'-anhydrothymidine 
• 94892-66-7 1-(2,5-dideoxy-5-iodo-β-D-threo-pentofuranosyl)thymine 
• 142409-83-4 1-[(2R,4R,5S)-5-Iodomethyl-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 142409-85-6 Methoxy-acetic acid (1R,10R,11R)-4-methyl-5-oxo-8,13-dioxa-2,6-diaza-tricyclo[8.2.1.0^2,7]trideca-3,6-dien-11-yl ester 
• 142409-82-3 Methoxy-acetic acid (2S,3R,5R)-2-iodomethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 

Downstream Products

• 135824-29-2 1-<3-O-(tert-butyldimethylsilyl)-2,5-dideoxy-5-(phenylseleno)-β-D-threo-pentofuranosyl>thymine 

Relevant academic research and scientific papers

Action of nucleophiles on 2,3'-anhydrothymidine: Side-reactions involving the possible intermediacy of 2,5'-anhydro-1-(2-deoxy-β-D-threo-pentofuranosyl)thymine

2,3'-Anhydrothymidine (1) reacts with the sodium salt of propane-2-thiol and with sodium phenyl selenide to give 5'-substituted products [(3b) and (3c), respectively] in addition to the expected 3'-substituted 2',3'-dideoxynucleoside derivatives [(2b) and

Preparation of γ- and δ-Phenylselenyl Alcohols via Ring Cleavage of Oxetane and Oxolane

Various types of oxetanes and oxolanes can be cleaved by reaction with phenylselenide anion prepared from diphenyl diselenide and lithium aluminum hydride in dioxane.

Cleavage of Cyclic Ethers Including Oxetane and Oxolane with a Highly Nucleophilic Species of Phenylselenide Anion

Phenylselenide anion generated from (PhSe)2 and LiAlH4 was found to be highly reactive to various types of cyclic ethers, providing a new method to prepare γ- and δ-phenylselenenyl alcohols from oxetane and oxolane, respectively.