117923-18-9Relevant articles and documents
1-Naphthylpiperazine derivatives as potential atypical antipsychotic agents
Lowe III,Seeger,Nagel,Howard,Seymour,Heym,Ewing,Newman,Schmidt,Furman,Vincent,Maloney,Robinson,Reynolds,Vinick
, p. 1860 - 1866 (2007/10/02)
The design and synthesis of a series of potential atypical antipsychotic agents based on the structure of 1-naphthylpiperazine are described. The incorporation of dopamine antagonist activity into the parent structure was achieved with heterocyclic surrog
Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds
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, (2008/06/13)
An arylpiperazinyl-alkylenephenyl-p-heterocyclic compound, useful in the treatment of psychotic disorders, of the formula- or a pharmaceutically-acceptable acid-addition salt thereof,wherein:-, Ar is phenyl, 3-trifluoromethylphenyl, 3-cyanopyridyl, naphth