117960-49-3

Upstream product

• 586-77-6 4-bromo-N,N-dimethylaniline 
• 117960-27-7 4-hydroxy-<4-(dimethylamino)phenyl>cyclohexanone ethylene ketal 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 619261-11-9 9-[4-(dimethylamino)phenyl]-3,3-dimethyl-1,5-dioxaspiro[5.5]undec-8-ene 
• 69225-59-8 3,3-dimethyl-1,5-dioxaspiro[5.5]undecan-9-one 
• 619261-12-0 4-(3,3-dimethyl-1,5-dioxaspiro[5.5]undec-9-yl)-N,N-dimethylaniline 
• 619261-10-8 9-[4-(dimethylamino)phenyl]-3,3-dimethyl-1,5-dioxaspiro[5.5]undecan-9-ol 

Downstream Products

• 117960-32-4 7-(4-Dimethylamino-phenyl)-1-methyl-3-oxo-2,3,5,6,7,8-hexahydro-isoquinoline-4-carbonitrile 
• 619261-15-3 2-{4-[4-(dimethylamino)phenyl]-1-hydroxycyclohexyl}-2-methylpropanoic acid 
• 117960-55-1 2-Acetyl-4-(4-dimethylamino-phenyl)-cyclohexanone 

Relevant academic research and scientific papers

Photoinduced charge separation in cyclohexylidene-based donor - (σ-bridge) - acceptor compounds - Building blocks for materials

We describe the syntheses and properties of five semi-rigid donor - (σ-bridge) - acceptor (D-σ-A) compounds. These compounds, which are candidates for incorporation in materials, have aniline-type donors and (mixed) cyano- and alkoxycarbonyl-1,1-difunctio

Cardiotonic Agents. 1-Methyl-7-(4-pyridyl)-5,6,7,8-tetrahydro-3(2H)-isoquinolinones and Related Compounds. Synthesis and Activity

A series of 1-methyl-7-(4-pyridyl)-5,6,7,8-tetrahydro-3(2H)-isoquinolinones and related compounds were synthesized and evaluated for positive inotropic activity.Most members of this series exerted a dose-dependent increase in myocardial contractility in the dog acute heart failure model, whereas they caused only slight changes in heart rate and blood pressure.Several derivatives, especially those with cyano, acetyl, and ethyl substituents at the 4-position, were more potent than milrinone, which was used as a reference. 4-Acetyl-1-methyl-7-(4-pyridyl)-5,6,7,8-tetrahydro-3(2H)-isoquinolinone (MS-857) is one of the most potent positive inotropic agents in this series.