117993-63-2Relevant academic research and scientific papers
Anticonvulsant Activity of Phenylmethylenehydantoins: A Structure-Activity Relationship Study
Thenmozhiyal, Jeyanthi Chinnappa,Wong, Peter Tsun-Hon,Chui, Wai-Keung
, p. 1527 - 1535 (2007/10/03)
Phenylmethylenehydantoins (PMHs) and their des-phenyl analogues were synthesized and evaluated for anticonvulsant activity using the maximal electroshock seizure (MES) assay. The phenyl rings of PMHs were substituted with a wide spectrum of groups, and th
REACTIONS OF CHLOROSULFONYLBENZYLIDENE HYDANTOINS
Cremlyn, Richard,Jethwa, Sanjay,Joiner, Graham,White, David
, p. 99 - 110 (2007/10/02)
5-(Benzylidene- and o-chlorobenzylidene-) and cinnamylidene-hydantoins reacted with chlorosulfonic acid to give the corresponding p-sulfonyl chlorides (1, 35, 44).These were converted into 49 derivatives by reaction with amines, hydrazines and azide ion.
