1179989-35-5Relevant academic research and scientific papers
Stereoselective synthesis of iriomoteolide-1a hemiketal core
Xie, Jun,Horne, David A.
, p. 4485 - 4487 (2009)
A stereoselective synthesis of the cyclic hemiketal core of iriometeolide-1a (1) is described. The key step involves a Sakurai reaction of allylsilane 4 and aldehyde 5, which bears a chiral α-tertiary center. Mild TES deprotection of β,γ-unsaturated keton
