118036-00-3

Upstream product

• 65567-06-8 lithium diphenylphosphide 
• 1079-66-9 chloro-diphenylphosphine 
• 117999-28-7 2-<2-(dimethylamino)ethyl>-1,3-propanediol 
• 5429-29-8 1,3-diethyl 2-[2-(dimethylamino)ethyl]propanedioate 
• 117999-39-0 {4-Diphenylphosphanyl-3-[(diphenylphosphanyl)-methyl]-butyl}-dimethyl-amine; hydrochloride 
• 117999-29-8 1,3-Dichloro-2-(2-dimethylaminoethyl)propane Hydrochloride 

Relevant academic research and scientific papers

Efficient 1,4-Asymetric Induction Utilizing Electrostatic Interaction between Ligand and Substrate in the Asymmetric Hydrogenation of Didehydrodipeptides

Electrostatic interaction between the amino group of the achiral 3-dimethylaminopropylidenebismethylenebis(diphenylphosphine) (1) and the carboxy group of the substrate enable an effective 1,4-asymmetric induction in the RhI-catalysed hydrogenation of didehydrodipeptides, to give (S,S)-or (R,R)-products selectively.The selectivity reached up to 94percent diastereoisomeric excess with acetyl didehydrodipeptides and 92percent with benzyloxycarbonyl substrates.