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1-(2-chloro-5-pyrazinyl)-1-propanone, a pyrazine derivative with the molecular formula C7H8ClN3O, is a colorless liquid featuring a pungent odor. It is synthesized by reacting 2-chloro-5-chloromethylpyrazine with propionyl chloride in the presence of a base, and is recognized for its versatile reactivity and functional groups, making it a valuable building block in organic synthesis.

118043-63-3

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118043-63-3 Usage

Uses

Used in Pharmaceutical Industry:
1-(2-chloro-5-pyrazinyl)-1-propanone is used as an intermediate for the synthesis of various drugs, leveraging its versatile reactivity and functional groups to contribute to the development of new pharmaceutical compounds.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, 1-(2-chloro-5-pyrazinyl)-1-propanone serves as an intermediate in the production of various agrochemicals, playing a crucial role in the synthesis of compounds that aid in crop protection and enhancement of agricultural yields.

Check Digit Verification of cas no

The CAS Registry Mumber 118043-63-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,0,4 and 3 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 118043-63:
(8*1)+(7*1)+(6*8)+(5*0)+(4*4)+(3*3)+(2*6)+(1*3)=103
103 % 10 = 3
So 118043-63-3 is a valid CAS Registry Number.

118043-63-3Downstream Products

118043-63-3Relevant academic research and scientific papers

Substituent-Directing Effects in the Homolytic Acylation of Pyrazine Derivatives

Houminer, Y.,Southwick, E. W.,Williams, D. L.

, p. 640 - 643 (1989)

The homolytic acylation of various monosubstituted pyrazines was studied for a wide spectrum of substituents.Methoxy and chloro substituents were found to direct ortho substitution, thus giving the corresponding 2,3-disubstituted pyrazines.Acetyl, carbethoxy, and carboxamide groups were found to direct para substitution, thus leading to the corresponding 2,5-disubstituted pyrazines.These selectivities result from the combination of the inductive and resonance effects of the substituents.The synthetic potential of the acylation reaction is demonstrated in the preparation of some novel pyrazine flavorants.

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