1180533-44-1

Basic information

• Product Name: 1-[3-[[(2-cyanoethoxy)(N,N-diisopropylamino)phosphino]oxymethyl]-5-(4,4'-dimethoxytrityloxymethyl)phenyl]uracil
• Synonyms: 1-[3-[[(2-cyanoethoxy)(N,N-diisopropylamino)phosphino]oxymethyl]-5-(4,4'-dimethoxytrityloxymethyl)phenyl]uracil
• CAS NO: 1180533-44-1
• Molecular Weight: 734.832
• Mol File: 1180533-44-1.mol

Chemical Properties

• CAS DataBase Reference: 1-[3-[[(2-cyanoethoxy)(N,N-diisopropylamino)phosphino]oxymethyl]-5-(4,4'-dimethoxytrityloxymethyl)phenyl]uracil(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3-[[(2-cyanoethoxy)(N,N-diisopropylamino)phosphino]oxymethyl]-5-(4,4'-dimethoxytrityloxymethyl)phenyl]uracil(1180533-44-1)
• EPA Substance Registry System: 1-[3-[[(2-cyanoethoxy)(N,N-diisopropylamino)phosphino]oxymethyl]-5-(4,4'-dimethoxytrityloxymethyl)phenyl]uracil(1180533-44-1)

Safety Data

• Hazardous Substances Data: 1180533-44-1(Hazardous Substances Data)

Upstream product

• 867259-26-5 1-[3-(4,4'-dimethoxytrityloxymethyl)-5-(hydroxymethyl)phenyl]uracil 
• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 

Relevant articles and documents

Synthesis and properties of a novel molecular beacon containing a benzene-phosphate backbone at its stem moiety

This paper describes the synthesis and properties of a novel molecular beacon (MB) containing a benzene-phosphate backbone at its stem moiety. The fluorescence intensity of MBs was found to stabilize by the introduction of the benzene-phosphate backbone at its stem moiety. Furthermore, an MB containing the benzene-phosphate backbone was more resistant to DNase I (endonuclease) than an MB comprising natural DNA and 2′-O-methyl-RNA. These results indicate that the MB with the benzene-phosphate backbone is superior as a molecular beacon as compared to the MB composed of natural DNA and 2′-O-methyl-RNA. The Royal Society of Chemistry 2009.