118074-07-0

Basic information

• Product Name: Clarithromycin Impurity Q (10 mg) (N-oxide clarithromycin)
• Synonyms: ClarithroMycin N-Oxide;6-O-Methylerythromycin N-oxide;Clarithromycin Impurity Q;Clarithromycin Impurity Q (10 mg) (N-oxide clarithromycin);Clarithromycin EP Impurity Q;Clarithromycin N-Oxide(EP Q)
• CAS NO: 118074-07-0
• Molecular Formula: C₃₈H₆₉NO₁₄
• Molecular Weight: 763.95276
• Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 118074-07-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: ?20°C
• Solubility: Chloroform (Slightly)
• PKA: 12.50±0.60(Predicted)
• CAS DataBase Reference: Clarithromycin Impurity Q (10 mg) (N-oxide clarithromycin)(CAS DataBase Reference)
• NIST Chemistry Reference: Clarithromycin Impurity Q (10 mg) (N-oxide clarithromycin)(118074-07-0)
• EPA Substance Registry System: Clarithromycin Impurity Q (10 mg) (N-oxide clarithromycin)(118074-07-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 118074-07-0(Hazardous Substances Data)

Upstream product

• 81103-11-9 clarithromycin 
• 992-65-4 erythromycin A N-oxide 
• 74-88-4 methyl iodide 

Downstream Products

• 81103-11-9 clarithromycin 
• 1185159-32-3 C₅₀H₇₄O₁₆S 

Relevant articles and documents

NEW MACROLIDES AND THEIR USE

The invention relates to macrolide compounds of formula (I),the use of said compounds as medicaments, in particular for the treatment or prevention of inflammatory and allergic diseases, pharmaceutical compositions containing said compounds and to process

Method of preparing clarithromycin

Clarithromycin can be easily prepared by reacting erythromycin A N-oxide with a methylating agent to obtain 6-O-methylerythromycin A N-oxide; and treating 6-O-methylerythromycin A N-oxide obtained above with a reducing agent in a high yield.