1180844-91-0Relevant articles and documents
Catalytic Enantioselective Vinylogous Allylic Alkylation of Coumarins
Kayal, Satavisha,Mukherjee, Santanu
, p. 4944 - 4947 (2017)
An unprecedented, organocatalytic enantioselective vinylogous γ-allylic alkylation of 4-methylcoumarins has been developed. Using allylic carbonates as the allyl source, this reaction is catalyzed by Lewis basic dimeric Cinchona alkaloid (QD)2P
Direct Synthesis of Dihydropyrrolo[2,1-a]Isoquinolines through FeCl3 Promoted Oxidative Aromatization
Cui, Hai-Lei,Jiang, Lu,Tan, Hao,Liu, Si
, p. 4772 - 4780 (2019/10/28)
We have developed a straightforward FeCl3 promoted synthesis of dihydropyrrolo[2,1-a]isoquinolines through formal (3+2) cycloaddition/oxidative aromatization cascade of dihydroisoquinoline with Morita-Baylis-Hillman carbonates (up to 96% yield)
Catalyst-free synthesis of skipped dienes from phosphorus ylides, allylic carbonates, and aldehydes via a one-pot SN2′ allylation-wittig strategy
Xu, Silong,Zhu, Shaoying,Shang, Jian,Zhang, Junjie,Tang, Yuhai,Dou, Jianwei
, p. 3696 - 3703 (2014/05/06)
A catalyst-free allylic alkylation of stabilized phosphorus ylides with allylic carbonates via a regioselective SN2′ process is presented. Subsequent one-pot Wittig reaction with both aliphatic and aromatic aldehydes as well as ketenes provides structurally diverse skipped dienes (1,4-dienes) in generally high yields and moderate to excellent stereoselectivity with flexible substituent patterns. This one-pot S N2′ allylation-Wittig strategy constitutes a convenient and efficient synthetic method for highly functionalized skipped dienes from readily available starting materials.
