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Ethyl 1,2,3,4-tetrahydroquinoline-8-carboxylate, commonly known as tetrahydroquinoline, is a chemical compound with the molecular formula C15H17NO2. It is a colorless liquid characterized by a strong odor. ethyl 1,2,3,4-tetrahydroquinoline-8-carboxylate is recognized for its versatile applications, particularly in the synthesis of pharmaceuticals and agrochemicals. Tetrahydroquinoline exhibits a range of pharmacological properties, such as antioxidant, anti-inflammatory, and analgesic effects, which contribute to its potential in various therapeutic areas. Moreover, it has been considered for the treatment of neurodegenerative diseases and cancer, and it also serves as a promising building block for the development of new drug candidates.

118128-79-3

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118128-79-3 Usage

Uses

Used in Pharmaceutical Synthesis:
Ethyl 1,2,3,4-tetrahydroquinoline-8-carboxylate is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of drugs with diverse therapeutic effects.
Used in Agrochemical Production:
In the agrochemical industry, ethyl 1,2,3,4-tetrahydroquinoline-8-carboxylate is utilized as a component in the creation of compounds designed to protect crops and enhance agricultural productivity.
Used in Antioxidant Applications:
Ethyl 1,2,3,4-tetrahydroquinoline-8-carboxylate is employed as an antioxidant agent, leveraging its ability to combat oxidative stress, which is beneficial in the prevention of cellular damage and the treatment of related conditions.
Used in Anti-inflammatory and Analgesic Formulations:
ethyl 1,2,3,4-tetrahydroquinoline-8-carboxylate is used as an anti-inflammatory and analgesic agent, capitalizing on its inherent properties to reduce inflammation and alleviate pain.
Used in Neurodegenerative Disease Treatment:
Ethyl 1,2,3,4-tetrahydroquinoline-8-carboxylate is studied for its potential role in the treatment of neurodegenerative diseases, due to its capacity to target and mitigate the underlying pathological processes.
Used in Cancer Therapy:
ethyl 1,2,3,4-tetrahydroquinoline-8-carboxylate is being investigated for its potential use in cancer therapy, where it may contribute to the inhibition of tumor growth and the enhancement of the effectiveness of existing cancer treatments.
Used in Drug Development:
As a building block in drug development, ethyl 1,2,3,4-tetrahydroquinoline-8-carboxylate is used for the creation of new drug candidates, highlighting its importance in the advancement of pharmaceutical research and innovation.

Check Digit Verification of cas no

The CAS Registry Mumber 118128-79-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,1,2 and 8 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 118128-79:
(8*1)+(7*1)+(6*8)+(5*1)+(4*2)+(3*8)+(2*7)+(1*9)=123
123 % 10 = 3
So 118128-79-3 is a valid CAS Registry Number.

118128-79-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl ester of 1,2,3,4-tetrahydroquinoline-8-carboxylic acid

1.2 Other means of identification

Product number -
Other names Ethyl 1,2,3,4-tetrahydroquinoline-8-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:118128-79-3 SDS

118128-79-3Relevant academic research and scientific papers

Palladium-catalyzed oxidative carbonylation of aromatic C-H bonds of N -alkylanilines with CO and alcohols for the synthesis of o -aminobenzoates

Chen, Ming,Ren, Zhi-Hui,Wang, Yao-Yu,Guan, Zheng-Hui

, p. 1258 - 1263 (2015/01/30)

A Pd(II)-catalyzed C-H monocarbonylation of N-alkylanilines for the synthesis of o-aminobenzoates has been developed. Various aliphatic alcohols and phenol were tolerated in the reaction to afford the corresponding o-aminobenzoates in good yields under mild balloon pressure of CO.

Reduction of Quinolinecarboxylic Acids by Raney Alloy

Gracheva, I. N.,Tochilkin, A. I.

, p. 65 - 67 (2007/10/02)

The heterocyclic nucleus in quinolinecarboxylic acids is reduced by Raney alloy (nickel-aluminium) in alkaline media to give 1,2,3,4-tetrahydro-2-,3-,4-,5-,6-, and 8-quinolinecarboxylic acids and 8-methyl-5-quinolinecarboxylic acid and their ethyl esters.

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