1181456-13-2

Basic information

• Product Name: 4-Ethyl-1,3-thiazole-2-carboxylic acid
• Synonyms: 4-Ethyl-1,3-thiazole-2-carboxylic acid;2-Carboxy-4-ethyl-1,3-thiazole
• CAS NO: 1181456-13-2
• Molecular Formula: C6H7NO2S
• Molecular Weight: 157.19028
• Mol File: 1181456-13-2.mol

Chemical Properties

• Boiling Point: 318.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.337±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 0.55±0.10(Predicted)
• CAS DataBase Reference: 4-Ethyl-1,3-thiazole-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Ethyl-1,3-thiazole-2-carboxylic acid(1181456-13-2)
• EPA Substance Registry System: 4-Ethyl-1,3-thiazole-2-carboxylic acid(1181456-13-2)

Safety Data

• Hazardous Substances Data: 1181456-13-2(Hazardous Substances Data)

Upstream product

• 79247-88-4 4-ethylthiazole-2-carboxylic acid ethyl ester 

Relevant articles and documents

HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS

Compounds of Formula (I) and Formula (II), pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.

An Infrared Study of Rotational Isomerism in Thiazole-2-carboxylates

A series of alkyl thiazole-2-carboxylates containing a range of substituents at the 4- and 5-positions has been prepared.Solutions of these esters (mostly new compounds) show well resolved doublets in the i.r.C=O region which arise from rotational isomers.The higher wavenumber components are assigned to the more polar carbonyl O,S-anti-s-trans-rotamers and the lower wavenumber components to the carbonyl O,S-syn-s-trans-forms.Small, but systematic, differences between the methyl esters are noted.