79247-88-4

Basic information

• Product Name: Ethyl 4,5-dimethyl-1,3-thiazole-2-carboxylate
• Synonyms: Ethyl 4,5-dimethyl-1,3-thiazole-2-carboxylate;Ethyl 4-ethyl-1,3-thiazole-2-carboxylate;4-Ethyl-thiazole-2-carboxylic acid ethyl ester;Ethyl 4-ethylthiazole-2-carboxylate;2-Thiazolecarboxylic acid, 4-ethyl-, ethyl ester
• CAS NO: 79247-88-4
• Molecular Formula: C8H11NO2S
• Molecular Weight: 185.24344
• Mol File: 79247-88-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethyl 4,5-dimethyl-1,3-thiazole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 4,5-dimethyl-1,3-thiazole-2-carboxylate(79247-88-4)
• EPA Substance Registry System: Ethyl 4,5-dimethyl-1,3-thiazole-2-carboxylate(79247-88-4)

Safety Data

• Hazardous Substances Data: 79247-88-4(Hazardous Substances Data)

Usage

General Description

Ethyl 4,5-dimethyl-1,3-thiazole-2-carboxylate, also known as DMTC, is a chemical compound with a molecular formula C9H13NO2S. It is commonly used in the synthesis of pharmaceuticals, agrochemicals, and fragrances due to its unique thiazole ring structure. DMTC is also used as a flavoring agent in the food industry, adding a sulfur-like, meaty note to various food products. It is a colorless to pale yellow liquid with a strong, pungent odor, and is considered to be a potential irritant to the skin and eyes. DMTC is commonly synthesized through the reaction of ethyl acetoacetate and 1,1-dimethylthiosemicarbazide under acidic conditions.

Upstream product

• 16982-21-1 ethyl 2-amino-2-thioxoacetate 
• 816-40-0 1-Bromo-2-butanone 
• 78-93-3 butanone 

Downstream Products

• 17626-72-1 4-ethylthiazole 
• 1181456-13-2 4-ethyl-1,3-thiazole-2-carboxylic acid 

Relevant articles and documents

HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS

Compounds of Formula (I) and Formula (II), pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.

An Infrared Study of Rotational Isomerism in Thiazole-2-carboxylates

A series of alkyl thiazole-2-carboxylates containing a range of substituents at the 4- and 5-positions has been prepared.Solutions of these esters (mostly new compounds) show well resolved doublets in the i.r.C=O region which arise from rotational isomers.The higher wavenumber components are assigned to the more polar carbonyl O,S-anti-s-trans-rotamers and the lower wavenumber components to the carbonyl O,S-syn-s-trans-forms.Small, but systematic, differences between the methyl esters are noted.