118221-29-7Relevant academic research and scientific papers
VILSMEIER-HAACK REACTION OF 2-AMINO-X-BENZOTHIAZOLES WITH N-PHENYLFORMAMIDE IN THE PRESENCE OF BENZENESULFONYL CHLORIDE
Lacova, Margita,Nga, Nguyen thi,Halgas, Jan
, p. 311 - 318 (2007/10/02)
2-Amino-X-benzothiazoles (X = H, 4-Cl, 6-Cl, 6-NO2, 6-CH3, 6-OCH3, 6-Br) react with N-phenylformamide and two equivalents of benzenesulfonyl chloride in pyridine, affording different products in dependence on the substituent X: N-(X-2-benzothiazolyl)formamidines, N-phenyl-N'-(X-2-benzothiazolyl)formamidines, N-phenyl-N',N''-bis(X-2-benzothiazolyl)triaminomethanes, N-(X-2-benzothiazolyl)benzenesulfonamides and N-2-((X-3-phenyliminomethyl)benzothiazolylidene)benzenesulfonamides.In the presence of one equivalent of benzenesulfonyl chloride, benzothiazoles I either do not react or are partially benzenesulfonated.
