1182278-46-1Relevant articles and documents
Highly regio- and stereoselective Heck reaction of allylic esters with arenediazonium salts: Application to the synthesis of kavalactones
Moro, Angelica Venturini,Cardoso, Flavio Sega Pereira,Correia, Carlos Roque Duarte
supporting information; experimental part, p. 3642 - 3645 (2011/02/25)
Image Presented A highly efficient palladium-catalyzed Heck reaction of allylic esters with arenediazonium salts is described. The reaction proceeds under mild conditions, with excellent to total regio- and stereochemical control and with retention of the traditional leaving group. Furthermore, the generality of the present methodology is illustrated by the short total synthesis of the natural kavalactones, yangonine, (±)-methysticin, and (±)-dihydromethysticin.
