118234-89-2Relevant articles and documents
The small peptide-catalyzed direct asymmetric aldol reaction in water
Dziedzic, Pawel,Zou, Weibiao,Hafren, Jonas,Cordova, Armando
, p. 38 - 40 (2007/10/03)
The asymmetric aldol reaction is a powerful method for forming carbon-carbon bonds. Small peptides with a primary amine as the catalytic residue catalyze asymmetric aqueous aldol reactions between unmodified ketones and aldehydes to furnish the corresponding aldol products with high ees. The high momodularity of the small peptides should enable the construction of several novel catalysts by combinatorial techniques for the aqueous asymmetric aldol reaction. The remarkably high difference in stereoselectivity between the peptide bond-formation was an important step towards the evaluation of asymmetric catalysis and homochilarity.
Diphenyl (2,3-dihydro-2-thioxo-3-benzoxazolyl)phosphonate: A new, reactive condensing agent for the synthesis of amides, esters, peptides, and β-lactams via condensation
Ueda,Mori
, p. 1636 - 1641 (2007/10/02)
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