1182367-75-4

Upstream product

• 573764-86-0 4-amino-3-methyl-2-trifluoromethylbenzonitrile 
• 194853-86-6 4-fluoro-2-(trifluoromethyl)benzonitrile 
• 74-88-4 methyl iodide 

Downstream Products

• 1182368-12-2 (2R,3S)-2-((4-cyano-2-methyl-3-(trifluoromethyl)phenyl)amino)-3-hydroxybutanoic acid 
• 1182367-78-7 (2R,3R)-2-(4-cyano-2-methyl-3-(trifluoromethyl)phenylamino)-3-hydroxybutanoic acid 
• 1354339-88-0 (R)-2-(4-cyano-2-methyl-3-(trifluoromethyl)phenylamino)-3-hydroxy-3-methylbutanoic acid 
• 1371609-02-7 (R)-2-((4-cyano-2-methyl-3-(trifluoromethyl)phenyl)amino)-3-hydroxypropanoic acid 
• 1371609-06-1 C₁₃H₉F₃N₂O₃ 
• 1371609-05-0 (S)-4-(4-(hydroxymethyl)-2-oxooxazolidin-3-yl)-3-methyl-2-(trifluoromethyl)benzonitrile 
• 1371609-04-9 (R)-methyl 3-(4-cyano-2-methyl-3-(trifluoromethyl)phenyl)-2-oxooxazolidine-4-carboxylate 
• 1371609-03-8 (R)-methyl 2-((4-cyano-2-methyl-3-(trifluoromethyl)phenyl)amino)-3-hydroxypropanoate 
• 1371608-55-7 3-methyl-4-((4S,5S)-5-methyl-2-oxo-4-((S)-2,2,2-trifluoro-1-hydroxyethyl)oxazolidin-3-yl)-2-(trifluoromethyl)benzonitrile 
• 1371608-56-8 3-methyl-4-((4S,5S)-5-methyl-2-oxo-4-((R)-2,2,2-trifluoro-1-hydroxyethyl)oxazolidin-3-yl)-2-(trifluoromethyl)benzonitrile 
• 1371609-31-2 C₁₄H₁₁F₃N₂O₃ 
• 1371609-30-1 4-((4S,5S)-4-(hydroxymethyl)-5-methyl-2-oxooxazolidin-3-yl)-3-methyl-2-(trifluoromethyl)benzonitrile 
• 1371609-29-8 (4R,5S)-methyl 3-(4-cyano-2-methyl-3-(trifluoromethyl)phenyl)-5-methyl-2-oxooxazolidine-4-carboxylate 
• 1371609-28-7 (2R,3S)-methyl 2-((4-cyano-2-methyl-3-(trifluoromethyl)phenyl)amino)-3-hydroxybutanoate 

Relevant academic research and scientific papers

SELECTIVE ANDROGEN RECEPTOR MODULATORS

This invention provides compounds of formula I, pharmaceutical compositions comprising a compound of formula I and a pharmaceutically acceptable excipient, methods of modulating the androgen receptor, methods of treating diseases beneficially treated by an androgen receptor modulator (e.g., sarcopenia, prostate cancer, contraception, type 2 diabetes related disorders or diseases, anemia, depression, and renal disease) and processes for making compounds and intermediates useful in the preparation of same.

Selective androgen receptor modulators

This invention provides compounds of formulas I, Ia, Ib, Ic, Id, Ie, and or salts thereof, pharmaceutical compositions comprising a compound of formulas I, Ia, Ib, Ic, Id, Ie, and a pharmaceutically acceptable excipient, methods of modulating the androgen receptor, methods of treating diseases beneficially treated by an androgen receptor modulator (e.g., sarcopenia, prostate cancer, contraception, type 2 diabetes related disorders or diseases, anemia, depression, and renal disease) and processes for making compounds of formulas I, Ia, Ib, Ic, Id, Ie, and intermediates useful in the preparation of same.