1182869-79-9Relevant academic research and scientific papers
Ridaifen-F conjugated with cell-penetrating peptides inhibits intracellular proteasome activities and induces drug-resistant cell death
Tanaka, Makoto,Zhu, Yunhao,Shionyu, Masafumi,Ota, Nozomi,Shibata, Natsumi,Watanabe, Chihiro,Mizusawa, Akihito,Sasaki, Ryuzo,Mizukami, Tamio,Shiina, Isamu,Hasegawa, Makoto
, p. 636 - 650 (2018/02/10)
Ridaifen-F (RID-F) potently inhibits proteolytic activities of the 20S proteasome but poorly inhibits those of the 26S proteasome. Here, we report preparation of several conjugates in which various peptides are connected to RID-F. Conjugates with peptides
HEMI-PHORBOXAZOLE A DERIVATIVES AND METHODS OF THEIR USE
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, (2011/02/24)
The present invention is directed to hemi phorboxazole A: and its stereoisomers, as well as derivatives of hemi phorboxazole A of formula I: wherein ring A is aryl or a 5- or 6-membered heteroaryl optionally substituted with one or more of halogen, -OH, o
Hemi-phorboxazole A: Structure confirmation, analogue design and biological evaluation
Smith III, Amos B.,Liu, Zhuqing,Hogan, Anne-Marie L.,Dalisay, Doralyn S.,Molinski, Tadeusz F.
, p. 3766 - 3769 (2011/03/19)
Image Presented A synthesis providing totally synthetic (+)-hemi-phorboxazole A (1), proceeding in two steps (85% yield) from known vinyl iodide precursor (+)-2, has been achieved in conjunction with the design, synthesis, and biological evaluation of two
