1182869-80-2Relevant academic research and scientific papers
HEMI-PHORBOXAZOLE A DERIVATIVES AND METHODS OF THEIR USE
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, (2011/02/24)
The present invention is directed to hemi phorboxazole A: and its stereoisomers, as well as derivatives of hemi phorboxazole A of formula I: wherein ring A is aryl or a 5- or 6-membered heteroaryl optionally substituted with one or more of halogen, -OH, o
Hemi-phorboxazole A: Structure confirmation, analogue design and biological evaluation
Smith III, Amos B.,Liu, Zhuqing,Hogan, Anne-Marie L.,Dalisay, Doralyn S.,Molinski, Tadeusz F.
, p. 3766 - 3769 (2011/03/19)
Image Presented A synthesis providing totally synthetic (+)-hemi-phorboxazole A (1), proceeding in two steps (85% yield) from known vinyl iodide precursor (+)-2, has been achieved in conjunction with the design, synthesis, and biological evaluation of two
