118319-69-0

Upstream product

• 79265-30-8 2-(trimethylsilyl)thiazole 
• 81801-08-3 4-O-benzyl-2,3-O-isopropylidene-aldehydo-D-erythrose 
• 141873-77-0 (1R,2R)-3-O-benzyl-1,2-O-isopropylidene-1-(2-thiazolyl)-1,2,3-propanetriol 
• 141873-79-2 (1R,2R)-1,2-O-isopropylidene-1-(2-thiazolyl)-1,2,3-propanetriol 
• 100-39-0 benzyl bromide 
• 81028-12-8 (4S,5R)-4-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane-5-carboxaldehyde 
• 141873-73-6 (1R,2R)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-1-(2-thiazolyl)-1,2,3-propanetriol 

Downstream Products

• 118319-73-6 ((4R,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-thiazol-2-yl-methanone 
• 141873-80-5 Acetic acid (R)-((4R,5R)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-thiazol-2-yl-methyl ester 

Relevant academic research and scientific papers

4-O-benzyl-2,3-O-isopropylidene-D-erythrose and -D-threose from 2,3-O-isopropylidene-D-glyceraldehyde via thiazole intermediates. Synthesis of 2-deoxykanosamine

The adduct derived from 2,3-O-isopropylidene-D-glyceraldehyde and 2-(trimethylsilyl)thiazole is readily converted into the title D-erythrose (50% overal yield) by selective protection of the hydroxy groups and cleavage of the thiazole ring; the D-threose

Iterative, Stereoselective Homologation of Chiral Polyalkoxy Aldehydes Employing 2-(Trimethylsilyl)thiazole as a Formyl Anion Equivalent. The Thiazole Route to Higher Carbohydrates

A new approach to long-chain sugars is demonstrated by the stereoselective conversion of D-glyceraldehyde acetonide (2a), L-threose acetonide (2b), and dialdogalactopyranose diacetonide (2h) into higher homologues up to C9, C7, and C