118378-07-7Relevant articles and documents
Tremorgenic indole alkaloids. The total synthesis of (-)-penitrem D
Smith III, Amos B.,Kanoh, Naoki,Ishiyama, Haruaki,Minakawa, Noriaki,Rainier, Jon D.,Hartz, Richard A.,Cho, Young Shin,Cui, Haifeng,Moser, William H.
, p. 8228 - 8237 (2007/10/03)
A convergent, stereocontrolled total synthesis of the architecturally complex tremorgenic indole alkaloid (-)-penitrem D (4) has been achieved. Highlights of the synthesis include an efficient, asymmetric synthesis of the western hemisphere; the stereocon
A Concise Route to the Penitrem Series of Tremorgenic Mycotoxins: Preparation of an Oxocane-Fused Indole
Haseltine, John,Visnick, Melean,Smith, Amos B.
, p. 6160 - 6162 (2007/10/02)
In this paper we record an efficient synthesis of tricyclic aniline 4, an advanced intermediated which embodies the B-C-D rings of penitrem D (1).In addition, a diminutive version of the natural product, hexacycle 10, was prepared.