1184103-46-5

Basic information

• Product Name: 6-benzenesulfonyl-3-dimethylaminomethylene-8-methyl-8-aza-bicyclo[3.2.1]octan-2-one
• Synonyms: 6-benzenesulfonyl-3-dimethylaminomethylene-8-methyl-8-aza-bicyclo[3.2.1]octan-2-one
• CAS NO: 1184103-46-5
• Molecular Weight: 334.439
• Mol File: 1184103-46-5.mol

Chemical Properties

• CAS DataBase Reference: 6-benzenesulfonyl-3-dimethylaminomethylene-8-methyl-8-aza-bicyclo[3.2.1]octan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-benzenesulfonyl-3-dimethylaminomethylene-8-methyl-8-aza-bicyclo[3.2.1]octan-2-one(1184103-46-5)
• EPA Substance Registry System: 6-benzenesulfonyl-3-dimethylaminomethylene-8-methyl-8-aza-bicyclo[3.2.1]octan-2-one(1184103-46-5)

Safety Data

• Hazardous Substances Data: 1184103-46-5(Hazardous Substances Data)

Upstream product

• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 1184103-00-1 2-chloro-5-[12-methyl-8-(phenylsulfonyl)-2-pyridin-4-yl-7,8,9,10-tetrahydro-61-1-7,10-epiminocyclo-hepta[e]pyrazolo[1,5-a]pyrimidin-3-yl]phenol 

Relevant articles and documents

Novel pyrazolopyrimidines as highly potent B-Raf inhibitors

A novel series of pyrazolo[1,5-a]pyrimidines bearing a 3-hydroxyphenyl group at C(3) and substituted tropanes at C(7) have been identified as potent B-Raf inhibitors. Exploration of alternative functional groups as a replacement for the C(3) phenol demons

FUSED TRICYCLIC PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF

Fused, tricyclic pyrazolo{1,5-a]pyrimidine compounds of formula A or of formula B: and pharmaceutically acceptable salts thereof are described, which selectively inhibit Raf kinase activity and are useful for treating disorders mediated by certain Raf kinases.