118430-65-2Relevant academic research and scientific papers
A STEREOSPECIFIC SYNTHESIS OF (4R)-4--4,N-DIMETHYL-L-THREONINE (MeBmt)
Rao, A. V. Rama,Dhar, T. G. Murali,Chakraborty, T. K.,Gurjar, M. K.
, p. 2069 - 2072 (1988)
The utility of readily obtainable cis-oxazolidinone derivative (14) has been explored for the efficient and stereospecific synthesis of (4R)-4--4,N-dimethyl-L-threonine, an unusual syn-β-hydroxy-α-amino acid of cyclosporine.
A VERSATILE PROTOCOL FOR β-HYDROXY-α-AMINO ACIDS: AN APPLICATION TO (4R)-4--4,N-DIMETHYL-L-THREONINE (MeBmt)
Rao, A. V. Rama,Dhar, T. G. Murali,Bose, D. Subhas,Chakraborty, T. K.,Gurjar, M. K.
, p. 7361 - 7370 (2007/10/02)
cis-Oxazolidinone derivative (30) readily realised from chiral 2,3-epoxy alcohol (27) had been exploited in the synthesis of (4R)-4--4,N-dimethyl-L-threonine (2), an unusual β-hydroxy-α-amino acid present in cyclosporin.The intrinsic featur
