1184397-84-9Relevant academic research and scientific papers
Cyano-borrowing: Titanium-catalyzed direct amination of cyanohydrins with amines and enantioselective examples
Li, Qian,Li, Qing-Hua,Li, Wan-Fang,Li, Zhao-Feng,Liu, Tang-Lin,Peng, Yun-Gui,Ren, Li-Qing,Tao, Jing
supporting information, p. 651 - 654 (2020/01/28)
The direct amination of cyanohydrins with amines via a catalytic cyano-borrowing reaction was developed. The transformation features broad substrate scope, excellent functional group compatibility, and very mild and simple operations. Moreover, a titanium
Nafion-Fe: A new efficient "green" lewis acid catalyst for the ketonic strecker reaction
Surya Prakash,Bychinskaya, Inessa,Marinez, Eric R.,Mathew, Thomas,Olah, George A.
, p. 303 - 312 (2013/05/09)
The synthesis of various α-aminonitriles, precursors of α-amino acids has been carried out in moderate to high yields and high purity by the Strecker reaction from ketones, aliphatic/aromatic amines and TMSCN using a new "green" Lewis acid catalyst, Nafion-Fe (iron Nafionate, Fe(III) salt of Nafion-H, a solid polymeric perfluoroalkanesulfonic acid) under conventional thermal as well as microwave conditions. Microwave and solvent-free conditions applied in this method shorten the reaction times, improve the yields and diminishes the formation of side products. Strecker reaction occurs smoothly with secondary aliphatic amines also under these conditions which is not common under conventional conditions.
