1184980-60-6 Usage
General Description
2,2,2-TRIFLUORO-1-(4-FLUOROPHENYL)ETHYLAMINE HYDROCHLORIDE is a chemical compound that consists of a trifluoromethyl group and a 4-fluorophenyl group attached to an ethylamine moiety. It is commonly used as a reagent in organic synthesis for the introduction of the trifluoromethyl group. It has applications in the pharmaceutical industry for the development of fluorinated drugs and in agrochemicals for the synthesis of bioactive compounds. It is typically sold as a white to off-white powder and is considered to be stable under normal conditions of use and storage. However, it should be handled with care and proper safety measures due to its potential irritant and harmful effects if ingested or inhaled.
Check Digit Verification of cas no
The CAS Registry Mumber 1184980-60-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,4,9,8 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1184980-60:
(9*1)+(8*1)+(7*8)+(6*4)+(5*9)+(4*8)+(3*0)+(2*6)+(1*0)=186
186 % 10 = 6
So 1184980-60-6 is a valid CAS Registry Number.
1184980-60-6Relevant articles and documents
Thermocontrolled benzylimine-benzaldimine rearrangement over Nafion-H catalysts for efficient entry into α-trifluoromethylbenzylamines
Prakash, G.K. Surya,Glinton, Kevin E.,Panja, Chiradeep,Gurung, Laxman,Battamack, Patrice T.,T?r?k, Béla,Mathew, Thomas,Olah, George A.
, p. 607 - 611 (2012/02/13)
Nafion-H and Nafion SAC-13 are efficient solid Br?nsted acid catalysts for the preparation of trifluoromethyl ketimines from benzylamines and trifluoromethylated ketones in high yields. A finely tuned benzylimine- benzaldimine rearrangement by facile 1,3-hydrogen shift has been achieved for the formation of fluorinated benzaldimines in high yields by careful optimization of reaction conditions including attempts under microwave conditions and a flow system. These α-trifluoromethylated benzaldimines are efficient precursors for pharmaceutically important α- trifluoromethylated benzylamines, accessed through their direct acid hydrolysis.
