1185019-97-9

Basic information

• Product Name: 2-Methoxy-4-nitrophenylboronic acid pinacol ester
• Synonyms: 2-Methoxy-4-nitrophenylboronic acid pinacol ester;2-(2-METHOXY-4-NITROPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
• CAS NO: 1185019-97-9
• Molecular Formula: C₁₃H₁₈BNO₅
• Molecular Weight: 297.112
• Mol File: 1185019-97-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Methoxy-4-nitrophenylboronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methoxy-4-nitrophenylboronic acid pinacol ester(1185019-97-9)
• EPA Substance Registry System: 2-Methoxy-4-nitrophenylboronic acid pinacol ester(1185019-97-9)

Safety Data

• Hazardous Substances Data: 1185019-97-9(Hazardous Substances Data)

Upstream product

• 52427-05-1 2-bromo-5-nitrophenol 
• 554-84-7 meta-nitrophenol 
• 5344-78-5 4-bromo-3-nitroanizole 
• 73183-34-3 bis(pinacol)diborane 
• 77337-82-7 1-bromo-2-methoxy-4-nitrobenzene 

Downstream Products

• 1235492-36-0 4-(2-methoxy-4-nitrophenyl)-6-methylpyridazine 1-oxide 
• 1413921-03-5 2-(2-isopropoxy-4-nitrophenyl)-5-(2-methoxy-4-nitrophenyl)furan 
• 1319068-75-1 4-(2-methoxy-4-nitrophenyl)-6-methylpyrimidine 
• 1079178-14-5 4-(2-methoxy-4-nitrophenyl)-1-methyl-1H-pyrazole 

Relevant articles and documents

Discovery, Structure-Activity Relationships, and in Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain

Effective treatment of chronic pain, in particular neuropathic pain, without the side effects that often accompany currently available treatment options is an area of significant unmet medical need. A phenotypic screen of mouse gene knockouts led to the d

AMINO-ACID ANILIDES AS SMALL MOLECULE MODULATORS OF IL-17

The present invention relates to a compound according to formula I (I) and pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.

GAMMA SECRETASE MODULATORS

The invention relates to compounds of formula wherein R1, R1′, R2, R3, n, A, and hetaryl are defined herein or to pharmaceutically active acid addition salts thereof. The present compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of β-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.