1185035-71-5 Usage
Description
Bicalutamide-d4 is intended for use as an internal standard for the quantification of bicalutamide by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.
Chemical Properties
BICALUTAMIDE-D4 is White Solid
Uses
BICALUTAMIDE-D4 is used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0
Check Digit Verification of cas no
The CAS Registry Mumber 1185035-71-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,5,0,3 and 5 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1185035-71:
(9*1)+(8*1)+(7*8)+(6*5)+(5*0)+(4*3)+(3*5)+(2*7)+(1*1)=145
145 % 10 = 5
So 1185035-71-5 is a valid CAS Registry Number.
