1185155-89-8Relevant academic research and scientific papers
SHMT INHIBITORS AND USES THEREOF
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Paragraph 00288, (2018/06/30)
The present invention provides compounds, compositions thereof, and methods of using the same.
Synthesis, Activity, and Docking Study of Novel Phenylthiazole-Carboxamido Acid Derivatives as FFA2 Agonists
Ma, Liang,Wang, Taijin,Shi, Min,Fu, Ping,Pei, Heying,Ye, Haoyu
, p. 26 - 37 (2016/07/09)
Free fatty acid receptor 2 (FFA2), also known as GPR43, is activated by short-chain fatty acids (SCFAs) that are mainly produced by the gut microbiota through the fermentation of undigested carbohydrates and dietary fibers. FFA2 currently appears to be a
Steric and electronic factors influence regio-isomeric thiazole formations between substituted benzothioamides and ethyl bromopyruvate
Liang, Jun,Soucy, Valerie Dorman,Tusi, Vickie,Liu, Yanzhou,Zhang, Birong,Lai, Yingjie,Magnuson, Steve,Zhu, Bingyan,Wang, Fangdao,Gu, Jinghao,Zhang, Qingfen,Wu, Yuan,Deng, Wei,Yang, Wenqian
, p. 1137 - 1146 (2014/08/05)
We observed unexpected thiazole 1B formation when 2,6- dichlorobenzothioamide 1 and ethyl bromopyruvate were reacted under basic conditions at elevated temperatures in ethanol. Thiazole 1B, regio-isomeric to that expected under conventional Hantzsch condi
