118525-36-3

Basic information

• Product Name: Sagittatosdie B
• Synonyms: Sagittatosdie B;3-[(6-Deoxy-2-O-beta-D-xylopyranosyl-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
• CAS NO: 118525-36-3
• Molecular Formula: C₃₂H₃₈O₁₄
• Molecular Weight: 646.63572
• Mol File: 118525-36-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 895.5±65.0 °C(Predicted)
• Appearance: /
• Density: 1.53
• PKA: 6.29±0.40(Predicted)
• CAS DataBase Reference: Sagittatosdie B(CAS DataBase Reference)
• NIST Chemistry Reference: Sagittatosdie B(118525-36-3)
• EPA Substance Registry System: Sagittatosdie B(118525-36-3)

Safety Data

• Hazardous Substances Data: 118525-36-3(Hazardous Substances Data)

Usage

General Description

Sagittatoside B is a naturally occurring chemical compound found in the herb Centella asiatica, also known as Gotu Kola. It belongs to a group of compounds called triterpenoids, which have been studied for their potential health benefits. Sagittatoside B has been found to have antioxidant, anti-inflammatory, and wound-healing properties. It has also been investigated for its potential neuroprotective effects, making it a subject of interest for research into potential treatments for conditions such as neurodegenerative diseases and cognitive decline. Additionally, Sagittatoside B has been studied for its potential anti-cancer effects, with research suggesting that it may inhibit the growth of certain types of cancer cells. Overall, Sagittatoside B shows promise as a natural compound with potential health benefits in a variety of areas.

Upstream product

• 110623-73-9 4'-methoxy-5-hydroxy-8-3,3-dimethylallylflavone 3-O-β-D-xylopyranosyl(1<*>2)α-L-rhamnopyranoside-7-O-β-D-glucopyranoside 

Relevant articles and documents

Characterization of a novel thermostable glucose-tolerant GH1 β-glucosidase from the hyperthermophile Ignisphaera aggregans and its application in the efficient production of baohuoside I from icariin and total epimedium flavonoids

The minor flavonoid baohuoside I from Herba epimedii has better bioactivities than its precursor compounds icariin and other major epimedium flavonoids. In this study, a novel β-glucosidase gene (Igag_0940) was cloned and expressed to improve the conversion efficiency in the process of baohuoside I production. For the first time, the recombinant IagBgl1 was purified and then identified uniquely as a trimer in GH 1 family protein from Archaea. The maximum activity of recombinant IagBgl1 was exhibited at 95 °C, pH 6.5, and it retained more than 70% after incubation at 90 °C for 4 h. IagBgl1 had a high catalytic activity towards icariin with a Kcat/Km ratio of 488.19 mM?1·s?1. Under optimized conditions (65 °C, pH 6.5, 0.8 U/mL enzyme, and 90 min), 10 g/L icariin was transformed into 7.564 g/L baohuoside I with a molar conversion of 99.48%. Meanwhile, 2.434 g/L baohuoside I was obtained from 10 g/L total epimedium flavonoids by a two-step conversion system built with IagBgl1 and two other thermostable enzymes. This is the first report of enzymatic conversion for producing baohuoside I by thermostable enzymes.