118575-96-5Relevant articles and documents
Renal vasodilators. The role of the 4-substituent in isoquinolin-3-ol cardiovascular agents: 4-Ureido derivatives of isoquinolin-3-ol with selective renal vasodilator properties
Kanojia,Lever Jr.,Press,Williams,Werblood,Giardino,Falotico,Tobia
, p. 990 - 997 (2007/10/02)
The synthesis and cardiovascular evaluation of a series of isoquinolin-3-ol derivatives bearing a variety of nitrogen substituents (amino, acylamino, carbamate, and ureido) at C-4 are described. Certain of these compounds have a selective renal vasodilati