1185854-75-4Relevant academic research and scientific papers
Synthesis of fused dihydro-pyrimido[4,3-d]coumarins using Biginelli multicomponent reaction as key step
Matache, Mihaela,Dobrota, Cristian,Bogdan, Niculina D.,Dumitru, Ioana,Ruta, Lavinia L.,Paraschivescu, Codruta C.,Farcasanu, Ileana C.,Baciu, Ion,Funeriu, Daniel P.
, p. 5949 - 5957 (2011/03/18)
A new efficient approach for the synthesis of functionalized dihydro-pyrimido[4,3-d]coumarins is described. Use of benzyl- or tert-butyl acetoacetate and various salicyl aldehydes in typical Biginelli multicomponent reactions provides esters that can be e
