118591-69-8

Basic information

• Product Name: 2,6-DIFLUORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE
• Synonyms: 2,6-DIFLUORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE;2,6-difluorobenzoyl chloride oxime
• CAS NO: 118591-69-8
• Molecular Formula: C₇H₄ClF₂NO
• Molecular Weight: 191.5625664
• Mol File: 118591-69-8.mol
• Article Data: 14

Chemical Properties

• Melting Point: 104-106
• Boiling Point: 271.3°Cat760mmHg
• Flash Point: 117.9°C
• Appearance: /
• Density: 1.43g/cm³
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.517
• PKA: 9.83±0.70(Predicted)
• CAS DataBase Reference: 2,6-DIFLUORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIFLUORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE(118591-69-8)
• EPA Substance Registry System: 2,6-DIFLUORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE(118591-69-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 118591-69-8(Hazardous Substances Data)

Usage

General Description

2,6-DIFLUORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE, also known as diflufenzopyr, is a chemical compound used as a herbicide. It belongs to the class of imidazole herbicides and is primarily used to control broadleaf weeds in agricultural and non-crop areas. Diflufenzopyr works by inhibiting the growth of weeds through interference with their hormone systems, specifically by disrupting the synthesis of auxin, a plant growth hormone. The compound is typically applied as a pre-emergence or post-emergence treatment on crop fields and non-agricultural sites to maintain weed control. While diflufenzopyr has an established track record of effectiveness as a herbicide, it is important to handle and use it with care due to its potential chemical hazards.

InChI:InChI=1/C7H4ClF2NO/c8-7(11-12)6-4(9)2-1-3-5(6)10/h1-3,12H/b11-7-

Upstream product

• 19064-16-5 2,6-difluoro-benzaldehyde oxime 
• 437-81-0 2,6-difluorobenzaldehyde 

Downstream Products

• 135073-80-2 5-(2,6-Difluorobenzoyl)-2'-deoxyuridine oxime 
• 132659-34-8 3-(2,6-Difluoro-phenyl)-4,5-dihydro-isoxazole-5-carboxylic acid methyl ester 
• 132659-40-6 3-(2,6-Difluoro-phenyl)-4,5-dihydro-isoxazole-4-carboxylic acid methyl ester 
• 487009-43-8 5-amino-3-(2,6-difluoro-phenyl)-isoxazole-4-carboxylic acid amide 
• 897646-06-9 5-amino-3-(2,6-difluorophenyl)-4-(4-pyrimidinyl)isoxazole 
• 334971-36-7 4-methoxycarbonyl-5-methyl-3-(2,6-difluorophenyl)isoxazole 

Relevant articles and documents

Triazole alcohol derivative as well as preparation method and application thereof

The invention relates to a triazole alcohol derivative as well as a preparation method and application thereof. The chemical structure of the triazole alcohol derivative is shown as a formula I, R1 represents a benzene ring or a substituted benzene ring, and substituent groups of the substituted benzene ring can be located at all positions of the benzene ring, can be mono-substituted or multi-substituted, and can be selected from a) halogen which is F and Cl; b) an electron withdrawing group which is cyano or trifluoromethyl; c ) a lower alkyl of 1-4 carbon atoms or a halogen substituted loweralkyl; and d) lower alkoxy of 1-4 carbon atoms or halogen substituted lower alkoxy. The compound of the invention has strong antifungal activity, has the advantages of low toxicity, wide antibacterial spectrum and the like, and can be used for preparing antifungal drugs.

COMPOUNDS FOR MODULATING FXR

Provided herein are compounds of Formula (I), a stereoisomer, enantiomer or a pharmaceutically acceptable salt thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).

ISOXAZOLYL-CARBONYLOXY AZABICYCLO[3.2.1]OCTANYL COMPOUNDS AS FXR ACTIVATORS

The disclosure relates to activators of FXR useful in the treatment of autoimmune disorders, liver disease, intestinal disease, kidney disease, cancer, and other diseases in which FXR plays a role, having the Formula (I): wherein L1, L2, A, B, R1, R2, R3, and R4 are described herein.