1185985-41-4Relevant articles and documents
Highly enantioselective organocatalytic Michael addition of nitroalkanes to 4-oxo-enoates
Lu, Hai-Hua,Wang, Xu-Fan,Yao, Chang-Jiang,Zhang, Jian-Ming,Wu, Hong,Xiao, Wen-Jing
, p. 4251 - 4253 (2011/03/19)
A useful Michael addition reaction using nitroalkanes as the nucleophile and 4-oxo-enoates as the Michael acceptor has been disclosed, and the reaction allows expedient access to functionalized chiral γ-keto esters in high yields and excellent enantioselectivities (up to 98% ee), with a low catalyst loading.